SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04660

Signal sequence   MKLGDWKFCLLLFQLMFLTNVCLS

Length  24

Organism  Tachypleus tridentatus (Japanese horseshoe crab)

UniProt ID  Q27085,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04660.cif

Structure  SPKB04660.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2864.57594

Aliphatic index  125.8333333

Isoelectric point  8.227980369

Charge (pH=7)   0.873891284

Topological polar surface area  964.39

Aromaticity  0.166666667

Average rotatable bonds  3.958333333

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  36

X logP energy  -1.7766

Hydropathy 



Literature Information


Title  A Limulus intracellular coagulation inhibitor with characteristics of the serpin superfamily. Purification, characterization, and cDNA cloning.

DOI  NA,

Publication Year  1994

PubMed ID  8276848,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.