SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04659

Signal sequence   MRTVLVALLALVALTQA

Length  17

Organism  Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina)

UniProt ID  Q26636,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04659.cif

Structure  SPKB04659.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1783.24624

Aliphatic index  189.4117647

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  674.37

Aromaticity  0

Average rotatable bonds  3.411764706

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  23

X logP energy  -3.52333

Hydropathy 



Literature Information


Title  Purification, characterization, and cDNA cloning of procathepsin L from the culture medium of NIH-Sape-4, an embryonic cell line of Sarcophaga peregrina (flesh fly), and its involvement in the differentiation of imaginal discs.

DOI  NA,

Publication Year  1994

PubMed ID  8195162,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.