SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04658

Signal sequence   MKSYTALLAVAILCLFAAVGVSG

Length  23

Organism  Rhodnius prolixus (Triatomid bug)

UniProt ID  Q26239,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04658.cif

Structure  SPKB04658.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2298.82744

Aliphatic index  144.3478261

Isoelectric point  8.522939048

Charge (pH=7)   0.934864135

Topological polar surface area  810.46

Aromaticity  0.086956522

Average rotatable bonds  3.173913043

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -5.007

Hydropathy 



Literature Information


Title  Purification, partial characterization, and cloning of nitric oxide-carrying heme proteins (nitrophorins) from salivary glands of the blood-sucking insect Rhodnius prolixus.

DOI  10.1074/jbc.270.15.8691,

Publication Year  1995

PubMed ID  7721773,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.