SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04656

Signal sequence   MRTLWIVAVLLVSVEG

Length  16

Organism  Deinagkistrodon acutus (Hundred-pace snake) (Agkistrodon acutus)

UniProt ID  Q1ZY03,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04656.cif

Structure  SPKB04656.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1786.20604

Aliphatic index  176.25

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  655.27

Aromaticity  0.0625

Average rotatable bonds  3.5625

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  22

X logP energy  -1.89173

Hydropathy 



Literature Information


Title  Molecular evolution and structure-function relationships of crotoxin-like and asparagine-6-containing phospholipases A2 in pit viper venoms.

DOI  10.1042/BJ20040125,

Publication Year  2004

PubMed ID  15032748,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.