SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04655

Signal sequence   MDFKIFLFLTAIFMIVGVTVSTA

Length  23

Organism  Holotrichia diomphalia (Korean black chafer)

UniProt ID  Q1HAY7,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04655.cif

Structure  SPKB04655.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2565.16734

Aliphatic index  131.3043478

Isoelectric point  6.337367167

Charge (pH=7)   -0.00186425

Topological polar surface area  847.76

Aromaticity  0.173913043

Average rotatable bonds  3.565217391

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  32

X logP energy  -1.851

Hydropathy 



Literature Information


Title  A novel 40-kDa protein containing six repeats of an epidermal growth factor-like domain functions as a pattern recognition protein for lipopolysaccharide.

DOI  10.4049/jimmunol.177.3.1838,

Publication Year  2006

PubMed ID  16849495,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.