SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04652

Signal sequence   MATDGITSRFGFNERRRTHNRNSCRILEDKMLAKLLLLALAGLTAA

Length  46

Organism  Aedes aegypti (Yellowfever mosquito) (Culex aegypti)

UniProt ID  Q16927,

Motif  1..46



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04652.cif

Structure  SPKB04652.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5147.02564

Aliphatic index  97.82608696

Isoelectric point  11.37786599

Charge (pH=7)   4.030751953

Topological polar surface area  2224.79

Aromaticity  0.043478261

Average rotatable bonds  3.869565217

Number of hydrogen bond donors  82

Number of hydrogen bond acceptors  72

X logP energy  -23.77328

Hydropathy 



Literature Information


Title  Analysis of a vitellogenin gene of the mosquito, Aedes aegypti and comparisons to vitellogenins from other organisms.

DOI  10.1016/0965-1748(95)00037-v,

Publication Year  1995

PubMed ID  7550249,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.