SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04646

Signal sequence   MRVVLLASAVLCLLAGQVLS

Length  20

Organism  Anguilla anguilla (European freshwater eel) (Muraena anguilla)

UniProt ID  Q08127,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04646.cif

Structure  SPKB04646.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2056.59634

Aliphatic index  190

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  761.67

Aromaticity  0

Average rotatable bonds  3.4

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  27

X logP energy  -4.60253

Hydropathy 



Literature Information


Title  Purification and characterization of presumed thyrotropic hormone subunits of a teleost fish, the eel (Anguilla anguilla)

DOI  NA,

Publication Year  1991

PubMed ID  1933511,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.