SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04641

Signal sequence   MFLKFCVVAFAICLSINLSEG

Length  21

Organism  Phlebotomus duboscqi (Sandfly)

UniProt ID  Q06K77,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04641.cif

Structure  SPKB04641.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2305.83674

Aliphatic index  130

Isoelectric point  6.13535235

Charge (pH=7)   -0.124485044

Topological polar surface area  792.19

Aromaticity  0.142857143

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  30

X logP energy  -3.4974

Hydropathy 



Literature Information


Title  High degree of conservancy among secreted salivary gland proteins from two geographically distant Phlebotomus duboscqi sandflies populations (Mali and Kenya).

DOI  10.1186/1471-2164-7-226,

Publication Year  2006

PubMed ID  16952314,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.