SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04632

Signal sequence   MARGGRLGLALGLLLALVLALRA

Length  23

Organism  Mus musculus (Mouse)

UniProt ID  Q05186,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04632.cif

Structure  SPKB04632.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2318.93914

Aliphatic index  186.9565217

Isoelectric point  12.801071

Charge (pH=7)   2.997974365

Topological polar surface area  889.22

Aromaticity  0

Average rotatable bonds  3.434782609

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  28

X logP energy  -4.69719

Hydropathy 



Literature Information


Title  Separation and sequencing of familiar and novel murine proteins using preparative two-dimensional gel electrophoresis.

DOI  10.1002/elps.11501501101,

Publication Year  1994

PubMed ID  7523108,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.