SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04631

Signal sequence   MELKFSTFLSLTLLFSSVLNPALS

Length  24

Organism  Pyrus communis (Pear) (Pyrus domestica)

UniProt ID  Q05091,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04631.cif

Structure  SPKB04631.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2659.17614

Aliphatic index  130

Isoelectric point  6.408795646

Charge (pH=7)   -0.000535612

Topological polar surface area  971.85

Aromaticity  0.125

Average rotatable bonds  3.583333333

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  36

X logP energy  -6.873

Hydropathy 



Literature Information


Title  Molecular characterization of a polygalacturonase inhibitor from Pyrus communis L. cv Bartlett.

DOI  10.1104/pp.102.1.133,

Publication Year  1993

PubMed ID  8108494,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.