SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04630

Signal sequence   GRLLLGSLLVSLESALSA

Length  18

Organism  Cavia porcellus (Guinea pig)

UniProt ID  Q04962,

Motif  <1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04630.cif

Structure  SPKB04630.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1799.14084

Aliphatic index  178.8888889

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  738.14

Aromaticity  0

Average rotatable bonds  3.388888889

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  25

X logP energy  -6.98153

Hydropathy 



Literature Information


Title  Primary structure of guinea-pig Hageman factor: sequence around the cleavage site differs from the human molecule.

DOI  10.1016/0167-4838(92)90014-5,

Publication Year  1992

PubMed ID  1390917,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.