SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04627

Signal sequence   MMPSTLSLCLMLAGLCSLVTS

Length  21

Organism  Didelphis virginiana (North American opossum) (Didelphis marsupialis virginiana)

UniProt ID  Q03044,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04627.cif

Structure  SPKB04627.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2171.73004

Aliphatic index  130

Isoelectric point  5.826007312

Charge (pH=7)   -0.125965132

Topological polar surface area  757.91

Aromaticity  0

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  33

X logP energy  -6.9659

Hydropathy 



Literature Information


Title  Opossum serum alpha 1-proteinase inhibitor: purification, linear sequence, and resistance to inactivation by rattlesnake venom metalloproteinases.

DOI  10.1021/bi00053a015,

Publication Year  1993

PubMed ID  8422360,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.