SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04622

Signal sequence   MKLSGISLWLLAASIVHA

Length  18

Organism  Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

UniProt ID  Q01682,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04622.cif

Structure  SPKB04622.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1910.34814

Aliphatic index  162.7777778

Isoelectric point  9.702001779

Charge (pH=7)   1.088598356

Topological polar surface area  689.2

Aromaticity  0.055555556

Average rotatable bonds  3.444444444

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  25

X logP energy  -3.1876

Hydropathy 



Literature Information


Title  The structural gene coding for thiamin-repressible acid phosphatase in Schizosaccharomyces pombe.

DOI  10.1007/BF00318392,

Publication Year  1990

PubMed ID  2249257,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.