SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04613

Signal sequence   MNDLLTRRLLTMGAAAAMLAAVLLLTPITVPAGYPGAVAPATA

Length  43

Organism  Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

UniProt ID  P9WP41,

Motif  1..43



Activity Information


Pathway  Tat

Natural/Artificial  Natural

Subcellular location  Cell surface

Secretion efficiency  NA

Type  Tat/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04613.cif

Structure  SPKB04613.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4279.18364

Aliphatic index  127.4418605

Isoelectric point  9.347625292

Charge (pH=7)   0.997573747

Topological polar surface area  1575.93

Aromaticity  0.023255814

Average rotatable bonds  3.023255814

Number of hydrogen bond donors  54

Number of hydrogen bond acceptors  57

X logP energy  -12.73106

Hydropathy 



Literature Information


Title  Two-dimensional electrophoresis for analysis of Mycobacterium tuberculosis culture filtrate and purification and characterization of six novel proteins.

DOI  10.1128/IAI.66.8.3492-3500.1998,

Publication Year  1998

PubMed ID  9673225,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.