SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04612

Signal sequence   MRALLLLGALLVSLESTVS

Length  19

Organism  Bos taurus (Bovine)

UniProt ID  P98140,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04612.cif

Structure  SPKB04612.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1986.44104

Aliphatic index  184.7368421

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  767.24

Aromaticity  0

Average rotatable bonds  3.526315789

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  27

X logP energy  -5.33053

Hydropathy 



Literature Information


Title  Isolation and characterization of bovine factor XII (Hageman factor).

DOI  10.1021/bi00629a036,

Publication Year  1977

PubMed ID  861210,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.