SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04611

Signal sequence   MCPGLWGTCFWLWGSLLWLSIGRS

Length  24

Organism  Rattus norvegicus (Rat)

UniProt ID  P97535,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04611.cif

Structure  SPKB04611.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2770.32274

Aliphatic index  97.5

Isoelectric point  8.231408964

Charge (pH=7)   0.874031556

Topological polar surface area  929.81

Aromaticity  0.208333333

Average rotatable bonds  3.375

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  33

X logP energy  -2.77053

Hydropathy 



Literature Information


Title  Serine phospholipid-specific phospholipase A that is secreted from activated platelets. A new member of the lipase family.

DOI  10.1074/jbc.272.4.2192,

Publication Year  1997

PubMed ID  8999922,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.