SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04608

Signal sequence   MKVVATILYLVVLAICGLGIHGAHPTHS

Length  28

Organism  Sambucus nigra (European elder)

UniProt ID  P93543,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04608.cif

Structure  SPKB04608.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2914.56344

Aliphatic index  149.6428571

Isoelectric point  8.544937489

Charge (pH=7)   1.207591408

Topological polar surface area  1033.21

Aromaticity  0.035714286

Average rotatable bonds  3.25

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  39

X logP energy  -5.6938

Hydropathy 



Literature Information


Title  Elderberry (Sambucus nigra) bark contains two structurally different Neu5Ac(alpha2,6)Gal/GalNAc-binding type 2 ribosome-inactivating proteins.

DOI  10.1111/j.1432-1033.1997.00648.x,

Publication Year  1997

PubMed ID  9183001,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.