SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04600

Signal sequence   MAKNFQSVLLLVCLSFLVIVSSPQNAVQA

Length  29

Organism  Galleria mellonella (Greater wax moth)

UniProt ID  P85213,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04600.cif

Structure  SPKB04600.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3120.75894

Aliphatic index  141.0344828

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  1191.72

Aromaticity  0.068965517

Average rotatable bonds  3.517241379

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  42

X logP energy  -10.091

Hydropathy 



Literature Information


Title  Purification, cDNA cloning and expression of an insect defensin from the great wax moth, Galleria mellonella.

DOI  10.1111/j.1365-2583.2004.00462.x,

Publication Year  2004

PubMed ID  14728668,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.