SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04599

Signal sequence   SGKYISWEDSCSYLQL

Length  16

Organism  Bufo gargarizans andrewsi (Andrew's toad) (Bufo andrewsi)

UniProt ID  P85045,

Motif  <1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04599.cif

Structure  SPKB04599.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1879.07104

Aliphatic index  73.125

Isoelectric point  4.184372876

Charge (pH=7)   -1.063764672

Topological polar surface area  780.7

Aromaticity  0.1875

Average rotatable bonds  3.75

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  28

X logP energy  -7.3064

Hydropathy 



Literature Information


Title  Purification of a lysozyme from skin secretions of Bufo andrewsi.

DOI  10.1016/j.cbpc.2005.10.001,

Publication Year  2006

PubMed ID  16309969,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.