SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04598

Signal sequence   MKFALFSVLVVLLIATFVAA

Length  20

Organism  Hybomitra bimaculata (Horse fly)

UniProt ID  P84843,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04598.cif

Structure  SPKB04598.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2153.73764

Aliphatic index  175.5

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  682.7

Aromaticity  0.15

Average rotatable bonds  3.4

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  0.5269

Hydropathy 



Literature Information


Title  Vasotab, a vasoactive peptide from horse fly Hybomitra bimaculata (Diptera, Tabanidae) salivary glands.

DOI  10.1242/jeb.02003,

Publication Year  2006

PubMed ID  16391356,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.