SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04597

Signal sequence   MIAFSLLCLAAVLRQSFG

Length  18

Organism  Naja kaouthia (Monocled cobra) (Naja siamensis)

UniProt ID  P84805,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04597.cif

Structure  SPKB04597.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1940.39234

Aliphatic index  141.1111111

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  703.47

Aromaticity  0.111111111

Average rotatable bonds  3.5

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  25

X logP energy  -4.10083

Hydropathy 



Literature Information


Title  Cobra venom contains a pool of cysteine-rich secretory proteins.

DOI  10.1016/j.bbrc.2004.12.154,

Publication Year  2005

PubMed ID  15670767,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.