SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04596

Signal sequence   MKAIIFFIGCLMLIDLVAG

Length  19

Organism  Tityus obscurus (Amazonian scorpion) (Tityus cambridgei)

UniProt ID  P84693,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04596.cif

Structure  SPKB04596.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2068.66494

Aliphatic index  169.4736842

Isoelectric point  6.160569088

Charge (pH=7)   -0.063838966

Topological polar surface area  650.44

Aromaticity  0.105263158

Average rotatable bonds  3.631578947

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  25

X logP energy  0.9311

Hydropathy 



Literature Information


Title  Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

DOI  10.1016/j.jchromb.2003.09.002,

Publication Year  2004

PubMed ID  15025998,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.