SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04594

Signal sequence   MIPEFLVVSCTLAALCHSVPLSLQ

Length  24

Organism  Rattus norvegicus (Rat)

UniProt ID  P84039,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04594.cif

Structure  SPKB04594.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2572.13424

Aliphatic index  142.0833333

Isoelectric point  5.358674626

Charge (pH=7)   -1.033280919

Topological polar surface area  905.03

Aromaticity  0.041666667

Average rotatable bonds  3.291666667

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  35

X logP energy  -5.8453

Hydropathy 



Literature Information


Title  Characterization of nucleotide pyrophosphatase-5 as an oligomannosidic glycoprotein in rat brain.

DOI  10.1016/s0006-291x(03)01454-2,

Publication Year  2003

PubMed ID  12927778,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.