SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04592

Signal sequence   MKFLYGTILIAFFLTVMIATHSEA

Length  24

Organism  Hottentotta tamulus (Eastern Indian scorpion) (Mesobuthus tamulus)

UniProt ID  P83400,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04592.cif

Structure  SPKB04592.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2718.30774

Aliphatic index  122.0833333

Isoelectric point  7.541810143

Charge (pH=7)   0.089523065

Topological polar surface area  925.77

Aromaticity  0.166666667

Average rotatable bonds  3.625

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  35

X logP energy  -2.5507

Hydropathy 



Literature Information


Title  Purification and characterization of a short insect toxin from the venom of the scorpion Buthus tamulus.

DOI  10.1016/s0014-5793(02)03326-4,

Publication Year  2002

PubMed ID  12297317,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.