SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04589

Signal sequence   MNRKLLFVTLMVTMLVMQPSEG

Length  22

Organism  Opistophthalmus carinatus (African yellow leg scorpion)

UniProt ID  P83313,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04589.cif

Structure  SPKB04589.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2539.16624

Aliphatic index  110.4545455

Isoelectric point  9.695027686

Charge (pH=7)   0.999461077

Topological polar surface area  937.72

Aromaticity  0.045454545

Average rotatable bonds  3.909090909

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  35

X logP energy  -5.72393

Hydropathy 



Literature Information


Title  Antibacterial and antifungal properties of alpha-helical, cationic peptides in the venom of scorpions from southern Africa.

DOI  10.1046/j.1432-1033.2002.03177.x,

Publication Year  2002

PubMed ID  12354111,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.