SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04587

Signal sequence   MSSGRLLLLLGLLTLWAELTPVSGL

Length  25

Organism  Ophiophagus hannah (King cobra) (Naja hannah)

UniProt ID  P82966,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04587.cif

Structure  SPKB04587.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2654.24664

Aliphatic index  171.6

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  969.07

Aromaticity  0.04

Average rotatable bonds  3.44

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  34

X logP energy  -5.08553

Hydropathy 



Literature Information


Title  Purification and characterization of a chymotrypsin inhibitor from the venom of Ophiophagus hannah (King Cobra).

DOI  10.1006/bbrc.2001.4878,

Publication Year  2001

PubMed ID  11350064,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.