General Information
SPKB ID SPKB04579
Signal sequence MKTLLLTLVVVTIVCLDLGYT
Length 21
Organism Bungarus candidus (Malayan krait)
UniProt ID P81783,
Motif 1..21
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04579.cif
Physicochemical Information
Molecular weight 2308.90384
Aliphatic index 185.2380952
Isoelectric point 6.157533513
Charge (pH=7) -0.06468938
Topological polar surface area 809.79
Aromaticity 0.047619048
Average rotatable bonds 3.571428571
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 31
X logP energy -2.5695
Hydropathy
Literature Information
Title Candoxin, a novel toxin from Bungarus candidus, is a reversible antagonist of muscle (alphabetagammadelta ) but a poorly reversible antagonist of neuronal alpha 7 nicotinic acetylcholine receptors.
Publication Year 2002
PubMed ID 11884390,
Patent ID NA,