SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04578

Signal sequence   MKFLYGVILIALFLTVMTATLSEA

Length  24

Organism  Hottentotta tamulus (Eastern Indian scorpion) (Mesobuthus tamulus)

UniProt ID  P81761,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04578.cif

Structure  SPKB04578.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2646.28204

Aliphatic index  150.4166667

Isoelectric point  6.402001171

Charge (pH=7)   -0.001386026

Topological polar surface area  897.09

Aromaticity  0.125

Average rotatable bonds  3.583333333

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  34

X logP energy  -2.0571

Hydropathy 



Literature Information


Title  Isolation and characterization of a novel lepidopteran-selective toxin from the venom of South Indian red scorpion, Mesobuthus tamulus.

DOI  10.1186/1471-2091-2-16,

Publication Year  2001

PubMed ID  11782289,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.