SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04573

Signal sequence   MKAVGAWLLCLLLLGLALQGAA

Length  22

Organism  Bos taurus (Bovine)

UniProt ID  P81264,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04573.cif

Structure  SPKB04573.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2225.82214

Aliphatic index  177.7272727

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  759.32

Aromaticity  0.045454545

Average rotatable bonds  3.318181818

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  27

X logP energy  -1.601

Hydropathy 



Literature Information


Title  A prolactin-releasing peptide in the brain.

DOI  10.1038/30515,

Publication Year  1998

PubMed ID  9607765,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.