SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04558

Signal sequence   MKKINAIILLSSLTSASVFA

Length  20

Organism  Escherichia coli (strain K12)

UniProt ID  P76773,

Motif  1..20



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04558.cif

Structure  SPKB04558.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2107.57974

Aliphatic index  146.5

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  812.5

Aromaticity  0.05

Average rotatable bonds  3.6

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  30

X logP energy  -6.919

Hydropathy 



Literature Information


Title  Protein folding in the periplasm in the absence of primary oxidant DsbA: modulation of redox potential in periplasmic space via OmpL porin.

DOI  10.1093/emboj/19.22.5980,

Publication Year  2000

PubMed ID  11080145,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.