SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04556

Signal sequence   MRTLWIMAVLLLGVEG

Length  16

Organism  Craspedocephalus gramineus (Bamboo pit viper) (Trimeresurus gramineus)

UniProt ID  P70090,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04556.cif

Structure  SPKB04556.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1802.26654

Aliphatic index  164.375

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  635.04

Aromaticity  0.0625

Average rotatable bonds  3.6875

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  22

X logP energy  -0.76543

Hydropathy 



Literature Information


Title  Purification and primary structure of a myotoxic lysine-49 phospholipase A2 with low lipolytic activity from Trimeresurus gramineus venom.

DOI  10.1016/0041-0101(95)00090-9,

Publication Year  1995

PubMed ID  8744986,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.