SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04554

Signal sequence   MKVESVTFLTLLGIGCVLS

Length  19

Organism  Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))

UniProt ID  P68638,

Motif  1..19



Activity Information


Pathway  NA

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04554.cif

Structure  SPKB04554.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2010.47804

Aliphatic index  148.4210526

Isoelectric point  6.231833229

Charge (pH=7)   -0.062510328

Topological polar surface area  731.36

Aromaticity  0.052631579

Average rotatable bonds  3.526315789

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  28

X logP energy  -4.7484

Hydropathy 



Literature Information


Title  Vaccinia virus encodes a secretory polypeptide structurally related to complement control proteins.

DOI  10.1038/335176a0,

Publication Year  1988

PubMed ID  3412473,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.