SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04550

Signal sequence   MKNTSILFILGLALLLVLAFEAQVGES

Length  27

Organism  Chilobrachys guangxiensis (Chinese earth tiger tarantula) (Chilobrachys jingzhao)

UniProt ID  P62520,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04550.cif

Structure  SPKB04550.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2891.50214

Aliphatic index  162.5925926

Isoelectric point  4.258147297

Charge (pH=7)   -0.998760489

Topological polar surface area  1067.41

Aromaticity  0.074074074

Average rotatable bonds  3.62962963

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  37

X logP energy  -5.3441

Hydropathy 



Literature Information


Title  Jingzhaotoxin-III, a novel spider toxin inhibiting activation of voltage-gated sodium channel in rat cardiac myocytes.

DOI  10.1074/jbc.M401387200,

Publication Year  2004

PubMed ID  15084603,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.