SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04549

Signal sequence   MKTLLLTMVVVTIVCLDLGYT

Length  21

Organism  Naja atra (Chinese cobra)

UniProt ID  P62375,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04549.cif

Structure  SPKB04549.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2326.93704

Aliphatic index  166.6666667

Isoelectric point  6.157533513

Charge (pH=7)   -0.06468938

Topological polar surface area  809.79

Aromaticity  0.047619048

Average rotatable bonds  3.619047619

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  32

X logP energy  -2.8625

Hydropathy 



Literature Information


Title  Amino acid sequence of a cardiotoxin-like basic polypeptide (CLBP) with low cytotoxic activity isolated from the venom of the Formosan cobra (Naja naja atra).

DOI  NA,

Publication Year  1985

PubMed ID  4091854,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.