SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04546

Signal sequence   MRNTARWAATLGLTATAVCGPLAGASLASPATAPA

Length  35

Organism  Streptomyces lividans

UniProt ID  P61153,

Motif  1..35



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04546.cif

Structure  SPKB04546.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3340.86334

Aliphatic index  84.28571429

Isoelectric point  10.52640717

Charge (pH=7)   1.936002961

Topological polar surface area  1350.64

Aromaticity  0.028571429

Average rotatable bonds  2.8

Number of hydrogen bond donors  49

Number of hydrogen bond acceptors  48

X logP energy  -17.94896

Hydropathy 



Literature Information


Title  Two novel Streptomyces protein protease inhibitors. Purification, activity, cloning, and expression.

DOI  NA,

Publication Year  1992

PubMed ID  1737780,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.