SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04545

Signal sequence   MTRFVLFISCFFLIGMIVEC

Length  20

Organism  Tityus obscurus (Amazonian scorpion) (Tityus cambridgei)

UniProt ID  P60215,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04545.cif

Structure  SPKB04545.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2369.98484

Aliphatic index  126.5

Isoelectric point  6.135737489

Charge (pH=7)   -0.124193321

Topological polar surface area  755.88

Aromaticity  0.2

Average rotatable bonds  3.8

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  29

X logP energy  -0.37883

Hydropathy 



Literature Information


Title  Scorpion toxins from Tityus cambridgei that affect Na(+)-channels.

DOI  10.1016/s0041-0101(01)00252-5,

Publication Year  2002

PubMed ID  11821128,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.