SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04541

Signal sequence   MRGATRVSIMLLLVTVSDC

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P58294,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04541.cif

Structure  SPKB04541.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2065.53554

Aliphatic index  133.1578947

Isoelectric point  8.54983383

Charge (pH=7)   0.936449445

Topological polar surface area  829.14

Aromaticity  0

Average rotatable bonds  3.631578947

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  30

X logP energy  -7.88816

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.