SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04540

Signal sequence   MNSKLTALIFLGLIAIAYC

Length  19

Organism  Pandinus imperator (Emperor scorpion)

UniProt ID  P56972,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04540.cif

Structure  SPKB04540.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2055.56454

Aliphatic index  159.4736842

Isoelectric point  8.522939048

Charge (pH=7)   0.934864135

Topological polar surface area  716.92

Aromaticity  0.105263158

Average rotatable bonds  3.526315789

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -2.6101

Hydropathy 



Literature Information


Title  Scorpine, an anti-malaria and anti-bacterial agent purified from scorpion venom.

DOI  10.1016/s0014-5793(00)01384-3,

Publication Year  2000

PubMed ID  10767415,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.