SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04539

Signal sequence   MAFVLSLLMALVLVSYGPGGSLG

Length  23

Organism  Ovis aries (Sheep)

UniProt ID  P56829,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04539.cif

Structure  SPKB04539.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2295.82374

Aliphatic index  148.2608696

Isoelectric point  6.093198033

Charge (pH=7)   -0.002866115

Topological polar surface area  775.65

Aromaticity  0.086956522

Average rotatable bonds  3.130434783

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  30

X logP energy  -3.9458

Hydropathy 



Literature Information


Title  High homology between a trophoblastic protein (trophoblastin) isolated from ovine embryo and alpha-interferons.

DOI  10.1016/0014-5793(88)80574-x,

Publication Year  1988

PubMed ID  3254170,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.