SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04537

Signal sequence   MRLILSLPVLVVVLSMVLEGPAPAQA

Length  26

Organism  Canis lupus familiaris (Dog) (Canis familiaris)

UniProt ID  P56595,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04537.cif

Structure  SPKB04537.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2717.40774

Aliphatic index  172.3076923

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  947.2

Aromaticity  0

Average rotatable bonds  3.269230769

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  34

X logP energy  -3.78493

Hydropathy 



Literature Information


Title  Mass spectral analysis of the apolipoproteins on dog (Canis lupus familiaris) high density lipoproteins. Detection of apolipoprotein A-II.

DOI  10.1016/j.cbd.2008.08.002,

Publication Year  2008

PubMed ID  20483223,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.