General Information
SPKB ID SPKB04535
Signal sequence RGSVDYKDDDDK
Length 12
Organism Pandinus imperator (Emperor scorpion)
UniProt ID P55927,
Motif <1..12
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04535.cif
Physicochemical Information
Molecular weight 1412.43264
Aliphatic index 24.16666667
Isoelectric point 4.156416688
Charge (pH=7) -2.001227073
Topological polar surface area 724.32
Aromaticity 0.083333333
Average rotatable bonds 4.083333333
Number of hydrogen bond donors 25
Number of hydrogen bond acceptors 23
X logP energy -9.14613
Hydropathy
Literature Information
Title Two novel toxins from the venom of the scorpion Pandinus imperator show that the N-terminal amino acid sequence is important for their affinities towards Shaker B K+ channels.
Publication Year 1996
PubMed ID 8660410,
Patent ID NA,