SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04535

Signal sequence   RGSVDYKDDDDK

Length  12

Organism  Pandinus imperator (Emperor scorpion)

UniProt ID  P55927,

Motif  <1..12



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04535.cif

Structure  SPKB04535.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1412.43264

Aliphatic index  24.16666667

Isoelectric point  4.156416688

Charge (pH=7)   -2.001227073

Topological polar surface area  724.32

Aromaticity  0.083333333

Average rotatable bonds  4.083333333

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  23

X logP energy  -9.14613

Hydropathy 



Literature Information


Title  Two novel toxins from the venom of the scorpion Pandinus imperator show that the N-terminal amino acid sequence is important for their affinities towards Shaker B K+ channels.

DOI  10.1007/s002329900084,

Publication Year  1996

PubMed ID  8660410,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.