SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04533

Signal sequence   MPASSYFLLFFFMNFFSPAQS

Length  21

Organism  Clarias gariepinus (North African catfish) (Silurus gariepinus)

UniProt ID  P53543,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04533.cif

Structure  SPKB04533.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2479.89314

Aliphatic index  46.66666667

Isoelectric point  6.093198033

Charge (pH=7)   -0.002866115

Topological polar surface area  815.07

Aromaticity  0.333333333

Average rotatable bonds  3.428571429

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  31

X logP energy  -3.7405

Hydropathy 



Literature Information


Title  Maturational gonadotropin from the African catfish, Clarias gariepinus: purification, characterization, localization, and biological activity.

DOI  10.1016/0016-6480(92)90039-m,

Publication Year  1992

PubMed ID  1426937,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.