SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04531

Signal sequence   MCVSRLVLLLGLLLCVGAQLSNG

Length  23

Organism  Sparus aurata (Gilthead sea bream)

UniProt ID  P51925,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04531.cif

Structure  SPKB04531.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2372.97134

Aliphatic index  177.826087

Isoelectric point  8.231408964

Charge (pH=7)   0.874031556

Topological polar surface area  892.06

Aromaticity  0

Average rotatable bonds  3.47826087

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  32

X logP energy  -6.68373

Hydropathy 



Literature Information


Title  Three forms of gonadotropin-releasing hormone characterized from brains of one species.

DOI  10.1073/pnas.91.25.12081,

Publication Year  1994

PubMed ID  7991588,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.