SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04530

Signal sequence   MAAKILALWLLLAGTVFPQGCC

Length  22

Organism  Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni)

UniProt ID  P51918,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04530.cif

Structure  SPKB04530.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2319.90984

Aliphatic index  137.7272727

Isoelectric point  8.229691165

Charge (pH=7)   0.873739834

Topological polar surface area  770.76

Aromaticity  0.090909091

Average rotatable bonds  3.272727273

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  29

X logP energy  -2.285

Hydropathy 



Literature Information


Title  Primary structure of solitary form of gonadotropin-releasing hormone (GnRH) in cichlid pituitary; three forms of GnRH in brain of cichlid and pumpkinseed fish.

DOI  10.1016/0167-0115(95)00014-3,

Publication Year  1995

PubMed ID  7644702,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.