SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04526

Signal sequence   MASRLTPLTLLLLLLLAGDRVTS

Length  23

Organism  Bos taurus (Bovine)

UniProt ID  P50448,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04526.cif

Structure  SPKB04526.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2468.03654

Aliphatic index  173.9130435

Isoelectric point  10.39776887

Charge (pH=7)   0.998424161

Topological polar surface area  956.98

Aromaticity  0

Average rotatable bonds  3.52173913

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  33

X logP energy  -6.80646

Hydropathy 



Literature Information


Title  Purification of a proteinase inhibitor from bovine serum with C1-inhibitor activity.

DOI  10.1016/0304-4165(87)90001-8,

Publication Year  1987

PubMed ID  3814612,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.