SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04522

Signal sequence   MAFHSLLLLGLASLLFVSDA

Length  20

Organism  Monodelphis domestica (Gray short-tailed opossum)

UniProt ID  P49141,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04522.cif

Structure  SPKB04522.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2118.56204

Aliphatic index  166

Isoelectric point  5.292257586

Charge (pH=7)   -0.910660126

Topological polar surface area  742.89

Aromaticity  0.1

Average rotatable bonds  3.4

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -3.0648

Hydropathy 



Literature Information


Title  Evolution of transthyretin in marsupials.

DOI  10.1111/j.1432-1033.1995.tb20402.x,

Publication Year  1995

PubMed ID  7851414,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.