SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04520

Signal sequence   MAASHSFAFVVCVLEIGALTA

Length  21

Organism  Oryctolagus cuniculus (Rabbit)

UniProt ID  P48747,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04520.cif

Structure  SPKB04520.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2137.53984

Aliphatic index  120.952381

Isoelectric point  5.36107726

Charge (pH=7)   -0.971306203

Topological polar surface area  771.99

Aromaticity  0.095238095

Average rotatable bonds  3.142857143

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  29

X logP energy  -5.7042

Hydropathy 



Literature Information


Title  Chimeras of human complement C9 reveal the site recognized by complement regulatory protein CD59.

DOI  10.1074/jbc.270.8.3483,

Publication Year  1995

PubMed ID  7533152,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.