SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04519

Signal sequence   MRPLWLLTLLLALSQA

Length  16

Organism  Rattus norvegicus (Rat)

UniProt ID  P47853,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04519.cif

Structure  SPKB04519.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1839.31264

Aliphatic index  183.125

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  652.27

Aromaticity  0.0625

Average rotatable bonds  3.625

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  22

X logP energy  -1.08203

Hydropathy 



Literature Information


Title  Peptidomics for Studying Limited Proteolysis.

DOI  10.1021/acs.jproteome.5b00820,

Publication Year  2015

PubMed ID  26479776,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.