SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04516

Signal sequence   MRLHHLLLALLFLVLSAGSGFT

Length  22

Organism  Bos taurus (Bovine)

UniProt ID  P46165,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04516.cif

Structure  SPKB04516.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2409.96144

Aliphatic index  164.0909091

Isoelectric point  10.55350111

Charge (pH=7)   1.17979917

Topological polar surface area  854.37

Aromaticity  0.090909091

Average rotatable bonds  3.545454545

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  30

X logP energy  -3.29473

Hydropathy 



Literature Information


Title  Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils.

DOI  NA,

Publication Year  1993

PubMed ID  8454635,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.