SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04513

Signal sequence   MSKVKGFIYKPLMVMLALLLVVVSPAGAG

Length  29

Organism  Paenibacillus thiaminolyticus (Bacillus thiaminolyticus)

UniProt ID  P45741,

Motif  1..29



Activity Information


Pathway  NA

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04513.cif

Structure  SPKB04513.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3033.86924

Aliphatic index  141.0344828

Isoelectric point  10.64292272

Charge (pH=7)   2.996248784

Topological polar surface area  999.29

Aromaticity  0.068965517

Average rotatable bonds  3.413793103

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  39

X logP energy  -2.6825

Hydropathy 



Literature Information


Title  Mechanistic studies on thiaminase I. Overexpression and identification of the active site nucleophile.

DOI  10.1074/jbc.271.7.3445,

Publication Year  1996

PubMed ID  8631946,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.